Research

Energy and the Environment

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We devel­op and utilise nov­el com­pu­ta­tion­al method­olo­gies to explore prob­lems in ener­gy gen­er­a­tion, stor­age and the envi­ron­ment. Cen­tral to this top­ic are advanced meth­ods capa­ble of solv­ing ther­moflu­ids gov­ern­ing equa­tions in extreme con­di­tions.

Involved peo­ple: Niko­laos Bem­pedelis
 

 

 

 

 

 

 

Micro- & nano-fluidics and Process Engineering

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Mul­ti­physics flu­id mechan­ics at the micro­scop­ic scale are fast becom­ing a major tech­nol­o­gy enabler. We devel­op method­olo­gies and con­cepts to study, dis­cov­er and opti­mize process­es and devices at these scales.

Involved peo­ple: Anjana Kothandara­man, Pan Xiang

 

 

 

Vascular Biomechanics & Minimally Invasive Therapies

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We inves­ti­gate process­es con­nect­ed with blood flow, throm­bo­sis, wall remod­el­ling, mechan­otrans­duc­tion, endothe­li­um bio­me­chan­ics as well as method­olo­gies to invent, design and opti­mise devices and pro­ce­dures that treat vas­cu­lar dis­ease using implants, in a min­i­mal­ly inva­sive set­ting.

Involved peo­ple: Dr. Tom Peach, Dr. Kate­ri­na Spranger, Daniel Baeriswyl, Han­nah Safi, Xizhuo Jiang

 

 

Recent high­lights:

Integrative Organ Modelling

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We devel­op method­olo­gies that address the chal­lenge of scale dis­par­i­ty and com­plex­i­ty, to mod­el the patho­phys­i­ol­o­gy of entire organs. Cen­tral to this effort is a nov­el mod­el­ling par­a­digm – Mul­ti­com­part­men­tal Poro­elas­tic­i­ty – that allows for cap­tur­ing microscale (cellular/molecular) process­es, and for embed­ding those seam­less­ly in the bio­me­chan­ics of the entire organ. The human brain, and asso­ci­at­ed dis­eases like demen­tia and hydro­cephalus, has been an organ that we have inves­ti­gat­ed using this mod­el­ling approach.

 

Involved peo­ple: Dr. John Var­dakis, Dr. Liwei Guo